Biodiversity conservation in developing countries is faced with many and mounting challenges, including increasing human–wildlife conflicts (HWCs). In Africa and other developing countries, increasing HWCs, particularly those adjacent to protected areas, can adversely affect local stakeholder perceptions and support for conservation. We analyzed HWC reports for multiple wildlife species compiled >23 years (1995–2017) from the Greater Tsavo Ecosystem (GTE) in Kenya to determine HWC trends. The GTE is the largest protected area in Kenya, covering 22,681 km2. Overall, 39,022 HWC