The giraffe restraint device manufactured at the Cheyenne Mountain Zoo has the capability to fully support the weight of an immobilized adult giraffe in an upright posture and allow physical restraint of giraffe. The unit has been used for either chemical or physical restraint 74 times in 22 months, on seven different adult giraffe, without animal or personnel injuries. Habituation and desensitization of the giraffe are critical prerequisites for the successful use of the giraffe restraint device. Yohimbine effectively reversed