Osseous cyst-like lesions (OCLLs) are commonly reported in equines (Watkins, 1999).They are uncommon in ruminants (Tyron and Farrow, 1999) and have never been documented in a giraffe. The aetiopathogenesis of OCLLs has not yet been conclusively determined. Currently there are two hypotheses; defective endochondral ossification or, that cyst development follows mechanical trauma in joints with existing trauma (Stromberg, 1979; Verschooten and DeMoor, 1982)