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Gravitational haemodynamics and oedema prevention in the giraffe

Because it is so tall, the giraffe, Giraffa camelopardalis, provides an important animal model for investigating adaptive mechanisms to orthostatic (gravitational) pressure changes. Previous physiological studies of the giraffe have concentrated on arterial blood pressures in the heart and neck. Briefly, these investigations revealed that arterial pressure near the giraffe heart is about twice that in humans, to provide more normal blood pressure and perfusion to the brain. Another important question is that of how giraffes avoid pooling of blood

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Haemodynamics of the jugular vein in the giraffe

Controversy cotinues over the haemodynamics of the circulation to and from the head of the giraffe. The recent study by Hargens et al. provides new information explaining the absence of oedema in the legs of the ambulant giraffe. But in sedated, standing giraffes the pressure gradient down the jugular vein is about one-tenth of, and in the opposite direction to, that expected for a standing column of blood. Hargens et al. suggest that compartmentalization of the blood in the vein

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